Sodium glycinate, also known as sodium aminoacetate
Sodium glycinate, also known as sodium aminoacetate, is a compound with the chemical formula C2H4NNaO2 and CAS registry number 6000-44-8. It is a white to off-white crystalline powder that is hygroscopic and easily soluble in water. Sodium glycinate is a non-essential amino acid primarily found in gelatin and silk fibroin and is used therapeutically as a nutrient. It also acts as a fast inhibitory neurotransmitter.
Chemical Properties
Molecular Formula: C2H4NNaO2
Molecular Weight: 99.06 g/mol
Density: 1.333 g/cm³ at 20°C
Boiling Point: 321°C at 101.325 kPa
pKa: 4.3 at 20°C
Storage Temperature: Inert atmosphere, room temperature
Health Benefits
Nutritional Support: Sodium glycinate is used as a nutrient and can help improve glycogen storage utilized in the synthesis of hemoglobin, collagen, and glutathione. It also facilitates the amelioration of high blood fat and uric acid levels.
Pharmaceutical Applications: It is used in the production of drugs and as a component in intravenous solutions. Sodium glycinate is also used as a buffering agent in pharmaceutical formulations.
Skin Conditioning: In personal care products, sodium glycinate is used for its skin conditioning characteristics. It moisturizes and strengthens the skin, providing a silky and pleasant skin feel.
Applications
Food Industry: Sodium glycinate is used as a food additive, flavoring agent, and buffering agent. It is particularly useful in gum products and meat products to enhance flavor and stability.
Pharmaceutical Industry: It is used in the synthesis of pharmaceuticals, particularly as a starting material for the production of other compounds. Sodium glycinate is also used in intravenous solutions to maintain electrolyte balance.
Cosmetics: Sodium glycinate is used in the formulation of cosmetics, such as shampoos and soaps, due to its skin conditioning properties. It helps to moisturize and strengthen the skin, providing a pleasant tactile sensation.
Safety and Hazards
GHS Classification: Sodium glycinate is not classified as a hazardous substance. It does not meet the GHS hazard criteria for 100% of all reports.
Hazardous Combustion Products: When combusted, it may produce carbon oxides, nitrogen oxides, and other irritating and toxic fumes.
Special Protective Equipment: In industrial settings, standard protective equipment such as gloves, goggles, and a lab coat is recommended to handle sodium glycinate.
Regulatory Compliance
REACH Registered Substance: Sodium glycinate is registered under the REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) regulation, ensuring its compliance with European chemical safety standards.
Australian Inventory of Industrial Chemicals: It is listed in the Australian Inventory of Industrial Chemicals, indicating its approval for use in Australia.
Conclusion
Sodium glycinate is a versatile compound with a wide range of applications in the food, pharmaceutical, and cosmetic industries. Its stability, solubility, and nutritional benefits make it a valuable component in various formulations. With its low hazard profile and regulatory compliance, sodium glycinate is a safe and effective choice for multiple uses. Whether used as a food additive, a pharmaceutical intermediate, or a cosmetic ingredient, sodium glycinate offers unique advantages and benefits.