Choline chloride (CAS NO: 67-48-1)
Choline chloride (CAS NO: 67-48-1) is a vital amino acid derivative with significant applications across various industries. This product description provides a detailed overview of its properties, synthesis methods, applications, and safety considerations.
Chemical Properties
Choline chloride is a white crystalline powder with a slight fishy odor. It is highly soluble in water and ethanol but insoluble in non-polar solvents like ether and benzene. The compound has a molecular weight of 139.63 g/mol and decomposes at temperatures between 302°C and 305°C. It exhibits a pH of 5-6 in a 10% aqueous solution and is relatively stable under normal conditions, though it is hygroscopic and should be stored in a sealed container in a dry environment.
Biological Functions
Choline chloride plays several crucial roles in biological systems. It serves as a essential nutrient for animals, supporting fat metabolism, preventing fat deposition in organs, and enhancing growth and feed efficiency. Additionally, it acts as a precursor for the synthesis of phospholipids and acetylcholine, a neurotransmitter involved in muscle function and memory.
Production Methods
Choline chloride can be synthesized through various methods, including the reaction of trimethylamine with chloroethanol or epoxyethane. The continuous production method involves the reaction of trimethylamine hydrochloride and epoxyethane in a reactor, producing a crude product that is further processed into marketable forms.
Applications
Choline chloride finds extensive use in animal feed as a growth promoter and feed efficiency enhancer. It is also utilized in the pharmaceutical industry for the preparation of various medications and as a nutrient supplement in parenteral nutrition formulations. In the cosmetic industry, it is incorporated into skincare products for its moisturizing and skin-conditioning properties.
Safety and Handling
Choline chloride is considered low toxicity but should be handled with care to avoid skin and eye contact. Proper storage in a cool, dry place and the use of appropriate protective equipment are recommended to ensure safety during handling.
Market Value and Applications
The demand for choline chloride continues to grow due to its diverse applications in animal feed, pharmaceuticals, cosmetics, and human nutrition. Its importance in supporting animal and human health ensures its demand across these sectors.
Conclusion
Choline chloride is a multifunctional compound with significant applications in various industries. Its roles in animal nutrition, human health, and industrial processes highlight its importance as a valuable chemical entity.













